Rutgers University School of Arts and Sciences Division of Life Sciences
 

Publications

Selected Publications

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NCBI PubMed list of Jay A. Tischfield's publications

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Tischfield, J.A.  Loss of heterozygosity or: how I learned to stop worrying and love mitotic recombination. Am. J. Hum. Genet. 61:955-999 (1997).
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\r\nTischfield, J.A.  A reassessment of the low molecular weight phospholipase A2 gene family in mammals. J. Biol. Chem. 272:17247-17250 (1997).

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Shao, C., Deng, L., Henegariu, O., Liang, L., Raikwar, N., Sahota, A., Stambrook, P.J., and Tischfield, J. A. Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice. Proc. Natl. Acad. Sci., USA 96: 9230-9235 (1999).

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Shao, C., Deng, L., Henegariu, O., Liang, L., Stambrook, P.J. and Tischfield, JA. Chromosome instability contributes to loss of heterozygosity in mice lacking p53. Proc. Natl. Acad. Sci., USA 97:7405-7410 (2000).

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Shao, C., Stambrook, P.J.,  Tischfield, J.A.  Mitotic recombination is surpressed by chromosomal divergence in hybrids of distantly related mouse strains.  Nature Genet. 28:169-172 (2001).

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Evan, A.P., Bledsoe, S.B.,  Connors, B.A., Deng, L., Liang, L., Shao, C., Fineberg, N.S., Grynpas, M.D., Stambrook, P. J., Shao, Y., Sahota, A., Tischfield, J.A. Sequential analysis of kidney stone formation in the Aprt knockout mouse.   Kidney Int. 60:910-923 (2001).

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Cervantes, R.B., Stringer, J.R., Shao C., Tischfield, J.A., Stambrook, P.J. Embryonic stem cells and somatic cells differ in mutation frequency and type.  Proc. Natl. Acad. Sci., USA 99:3586-3590 (2002).

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Shao, C., Yin M., Deng, L., Stambrook, P.J., Doetschman T. and Tischfield, JA. Loss of heterozygosity and point mutation at Aprt locus in T cells and fibroblasts of Pms2-/- mice. Oncogene 21:2840-2845 (2002).

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Liang, L., Shao, C., Deng, L., Mendonca MS, Stambrook, PJ, Tischfield, J.A.  Radiation-induced genetic instability in vivo depends on p53 status.  Mutat Res 502(1-2):69-80, 2002.

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Porjesz, B., Almasy, L., Edenberg, H.J., Wang, K., Chorlian, D.B., Foroud, T., Goate, A., Rice, J.P., O’Connor, S.J., Rohrbaugh, J., Kuperman, S., Bauer L.O., Crowe, R.R., Schuckit, M.A., Hesselbrock, V., Conneally, P.M., Tischfield, J.A., Li, T-K, Reich, T., and Begleiter, H.  Linkage Disequilibrium between the Beta Frequency of the Human EEG and a GABAA receptor gene locus. Proc Natl Acad Sci USA 99:3729-3733 (2002).

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Tischfield, JA, Shao, C.  Somatic recombination redux.  Nature Genet. 33:5-6 (2003).

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Mlh1 mediates tissue-specific regulation of mitotic recombination. 2004 Dec 2;23(56):9017-24.

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Liang, L., Deng, L., Chen, Y., Li, GC, Shao, C., Tischfield, J.A.  Modulation of DNA end joining by nuclear proteins.  J Biol Chem. 2005 Sep 9;280(36):31442-9.  Epub 2005 Jul 11.

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Vernon HJ, Osborne C, Tzortzaki EG, Yang M, Chen J, Rittling SR, Denhardt DT, Buyske S, Bledsoe SB, Evan AP, Fairbanks L, Simmonds HA, Tischfield.  Aprt/Opn double knockout mice: osteopontin is a modifier of kidney stone disease severity. Kidney Int. 2005 Sep;68(3):938-47.

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Edenberg HJ, Xuei X, Chen HJ, Tian H, Wetherill LF, Dick DM, Almasy L, Bierut L, Bucholz KK, Goate A, Hesselbrock V, Kuperman S, Nurnberger J, Porjesz B, Rice J, Schuckit M, Tischfield J, Begleiter H, Foroud T. Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Hum Mol Genet. 2006 May 1;15(9):1539-49. Epub 2006 Mar 28.

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Liang L, Mendonca MS, Deng L, Nguyen SC, Shao C, Tischfield JA. Reduced apoptosis and increased deletion mutations at Aprt locus in vivo in mice exposed to repeated ionizing radiation. Cancer Res. 2007 Mar 1;67(5):1910-7.

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Liang L, Deng L, Mendonca MS, Chen Y, Zheng B, Stambrook PJ, Shao C, Tischfield JA. X-rays induce distinct patterns of somatic mutation in fetal versus adult hematopoietic cells. DNA Repair (Amst). 2007 Sep 1;6(9):1380-5. Epub 2007 Jun 5.

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Edenberg HJ, Wang J, Tian H, Pochareddy S, Xuei X, Wetherill L, Goate A, Hinrichs T, Kuperman S, Nurnberger JI Jr, Schuckit M, Tischfield JA, Foroud T. A regulatory variation in OPRK1, the gene encoding the {kappa}-opioid receptor, is associated with alcohol dependence. Hum Mol Genet. 2008 Mar 4. [Epub ahead of print].

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Liang L, Deng L, Nguyen SC, Zhao X, Maulion CD, Shao C, Tischfield JA. Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks. Nucleic Acids Res. 2008 Apr 24. [Epub ahead of print].