Rutgers University School of Arts and Sciences Division of Life Sciences
 

Publications

View full list of Dr. Heiman's publications in Google Scholar

 

  1. Heiman GA, Hodge SE, Wickramaratne P, and Hsu H. Age-at-interview bias in anticipation studies: computer simulations and an example with panic disorder. Psychiat Genet 6: 61—66, 1996.
  2. Hamilton SP, Heiman GA, Haghigi F, Mick S, Klein DF, Hodge SE, Weissman MM, Fyer AJ, and Knowles JA.  Lack of genetic linkage or association between a functional serotonin transporter polymorphism and panic disorder. Psychiat Genet 9: 1—6, 1999.

  3. Kramer P, Heiman GA, Gasser T, Ozelius L, DeLeon D, Brin MF, Burke R, Hewett J, Hunt A, Moskowitz CB, Nygaard T, Wilhelmsen K, Fahn S, Breakefield XO, Risch NJ, and Bressman SB. The DYT1 gene on 9q34 is responsible for most cases of early limb-onset idiopathic torsion dystonia in non-Jews. Am J Hum Genet 55:468–475, 1994. Manuscript: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1918396/

  4. Bressman SB, Hunt A, Heiman GA, Brin MF, Burke R, Fahn S, Trugman J, DeLeon D, Kramer P, Wilhelmsen K, and Nygaard T. Exclusion of the DYT1 locus in a non-Jewish family with early-onset Dystonia. Mov Disord 9:626–632, 1994.

  5. Heiman GA, Hodge SE, Wickramaratne P, and Hsu H. Age-at-interview bias in anticipation studies: computer simulations and an example with panic disorder. Psychiat Genet 6:61–66, 1996. Manuscript: http://genfaculty.rutgers.edu/uploads/2/Heiman1996-anticipation.pdf

  6. Bressman SB, Warner TT, Almasy L, Uitti RJ, Greene PE, Heiman GA, Raymond D, Ford B, de Leon D, Fahn S, Kramer P, Risch NJ, Maraganore DM, Nygaard TG, and Harding AE. Exclusion of the DYT1 locus in familial torticollis. Ann Neurol 40:681–684, 1996. Manuscript: https://genfaculty.rutgers.edu/uploads/2/Bressman1994-Exclusion%20of%20DYT1.pdf

  7. Almasy L, Bressman SB, Raymond D, Kramer P, Greene PE, Heiman GA, Ford B, Yount BA, de Leon D, Chouinard S, Saunders-Pullman R, Brin MF, Kapoor RP, Jones AC, Shen H, Fahn S, Risch NJ, and Nygaard TG. Idiopathic torsion dystonia linked to chromosome 8 in two Mennonite families. Ann Neurol 42:670–673, 1997. Manuscript: http://genfaculty.rutgers.edu/uploads/2/Almasy1997.pdf

  8. Knowles JA, Fyer AJ, Vieland VJ, Weissman MM, Hodge SE, Heiman GA, Haghighi F, de Jesus GM, Rassnick H, Preud'homme-Rivelli X, Austin T, Cunjak J, Mick S, Fine LD, Woodley KA, Das K, Maier W, Adams PB, Freimer NB, Klein DF, and Gilliam TC. Results of a genome-wide genetic screen for panic disorder. Am J Med Genet B (Neuropsychiat Genet) 81:139–147, 1998. Manuscript: http://genfaculty.rutgers.edu/uploads/2/Knowles1998.pdf

  9. Nygaard TG, Raymond D, Chen C, Nishino I, Greene PE, Jennings D, Heiman GA, Klein C, Saunders-Pullman RJ, Kramer P, Ozelius LJ, and Bressman SB. Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31. Ann Neurol 46:794–798, 1999. Manuscript: http://genfaculty.rutgers.edu/uploads/2/Nygaard1999.pdf

  10. Weissman MM, Fyer AJ, Haghigi F, Heiman GA, Deng Z, Hen R, Hodge SE, and Knowles JA.  A potential panic disorder syndrome: clinical and genetic linkage evidence. Am J Med Genet B (Neuropsychiatr Genet) 96:24—35, 2000. Manuscript: http://www.ncbi.nlm.nih.gov/pubmed/10686548 

  11.  Hamilton SP, Haghigi F, Heiman GA, Klein DF, Hodge SE, Fyer AJ, Weissman MM, and Knowles JA. Investigation of Dopamine Receptor (DRD4) and Dopamine Transporter (DAT) Polymorphisms for Genetic Linkage or Association to Panic Disorder. Am J Med Genet B (Neuropsychiatr Genet) 96:324–330, 2000. Manuscript: http://www.ncbi.nlm.nih.gov/pubmed/10898909

  12. Saunders-Pullman R, Shriberg J, Heiman GA, Raymond R, Wendt K, Kramer P,  Schilling K, Kurlan R, Klein C, Ozelius LJ, Risch NJ, PhD and Bressman SB.  The spectrum of myoclonus dystonia: Possible association with OCD and alcohol dependence. Neurology 58: 242-245, 2002.

  13. Hamilton SP, Fyer AJ, Durner, M, Heiman GA, de Leon AB, Hodge SE, Knowles JA, and Weissman MM.  Further genetic evidence for a panic disorder syndrome mapping to chromosome 13q.  Proc Natl Acad Sci 100(5): 2550-2555, 2003.

  14. Weissman MM, Gross R, Fyer, AF, Heiman GA, Gameroff MJ, Hodge SE, Kaufman D, Kaplan SA and Wickramaratne P. Interstitial cystitis and panic disorder: A potential genetic syndrome. Arch Gen Psych 61:273 - 279, 2004.

  15. Heiman GA, Ottman R, Saunders-Pullman R, Ozelius LJ, Risch NJ, and Bressman SB.  Increased risk for recurrent major depression in DYT1 dystonia mutation carriers. Neurology 63(4): 631-637, 2004.

  16. Heiman GA, Hodge SE, Gorroochurn P, Zhang J, and Greenberg DA. Effect of population stratification on case-control association studies. I: elevation in false positive rates and comparison to confounding risk ratios (a simulation study). Hum Hered 58:30-39, 2004.

  17. Gorroochurn P, Hodge SE, Heiman GA, and Greenberg DA. Effect of population stratification on case-control association studies. II: false-positive rates and their limiting behavior as number of subpopulations increases. Hum Hered 58:40-48, 2004.

  18. Gorroochurn P, Heiman GA, Hodge SE, and Greenberg DA. Centralizing the non-central chi-square: a new method to correct for population stratification in genetic case-control association studies. Genet Epidemiol 30: 277-289, 2006.

  19. Fyer A.J, Hamilton SP, Durner M, Haghighi F, Heiman GA, Costa R, Evrafov O, Adams P, deLeon A, Taveras N, Klein DF, Hodge SE, Weissman MM, and Knowles JA. A Third-Pass Genome Scan in Panic Disorder: Evidence for Multiple Susceptibility Loci. Biol Psychiatry 60(4): 388-401, 2006.

  20. Hess CW, Raymond D, de Carvalho Aguiar P, Frucht S, Shriberg J, Heiman GA, Kurlan R, Klein C, Bressman SB, Ozelius LF, and Saunders-Pullman R.  Myoclonus-dystonia and the association with obsessive-compulsive disorder and alcohol dependence in manifesting SGCE carriers. Neurology 68: 522–524, 2007. 

  21. Gorroochurn P, Hodge SE, Heiman GA, Durner M, and Greenberg DA. Non-replication in association studies: 'pseudo-failures' to replicate? Genet Med 9: 325-331, 2007.

  22. Heiman GA, Ottman R, Saunders-Pullman R, Ozelius LJ, Risch NJ, and Bressman SB.  Obsessive-compulsive disorder is not a manifestation of the DYT1 dystonia mutation.  Am J Med Genet Part B (Neuropsychiatr Genet) 144B:361–364, 2007.

  23. Heiman GA, Ogburn B, Gorroochurn P, Keyes K, and Hasin, DS. Evidence for a two-stage model of dependence using the NESARC and its implications for genetic association studies. Drug Alcohol Depend. 92: 258–266, 2008.

  24. Choi H, Heiman GA, Pandis D, Cantero J, Resor SR, Gilliam FG, and Hauser WA. Seizure Remission and Relapse in Adults with Intractable Epilepsy: A Cohort Study. Epilepsia 49(8):1440–1445, 2008.

  25. Heiman GA, King RA, and Tischfield JA. New Jersey Center for Tourette Syndrome Sharing Repository: methods and sample description.  BMC Medical Genomics 1:58, 2008.  URL: http://www.biomedcentral.com/1755-8794/1/58

  26. Logue MW, Durner M, Heiman GA, Hodge SE, Hamilton SP, Knowles JA, Fyer AJ, and Weissman MM. Bipolar and Panic Disorder: Common and Syndrome-Specific Genes? Am J Med Genet Part B (Neuropsychiatr Genet), 2009 (Published online: 3/23/2009; DOI:10.1002/ajmg.b.30939).

  27. Bressman SB, Raymond D, Fuchs T, Heiman GA, Ozelius LJ, and Saunders-Pullman R.  THAP1 (DYT6) mutations in early-onset primary dystonia. Lancet Neurol. 8: 441–46, 2009.

  28. Choi H, Carlino RF, Heiman GA, Hauser WA, and Gilliam F.  Evaluation of duration of epilepsy prior to temporal lobe epilepsy surgery during the past two decades.  Epilepsy Research, 2009 (Published online: doi:10.1016/j.eplepsyres. 2009.05.014).

  29. Ercan-Sencicek AG, Stillman AA, Ghosh A, Bilguvar K,. O’Roak BJ,. Mason CE, Abbott T, Gupta A, King RA, Pauls DL, Tischfield JA, Heiman GA, Singer HS, Gilbert DL, Hoekstra PJ, Loring E, Yasuno K, Fernandez T, Sanders S, Louvi A, Cho JH, Mane S, Colangelo CM, Biederer T,. Lifton RP, Gunel M and State MW.  A rare dominant negative mutation in L-histidine decarboxylase (HDC) implicates histaminergic neurotransmission in Tourette syndrome (TS).  N Engl J Med, 362:1901-8, 2010. PMCID: PMC2894694.

  30. Heiman GA, Kamberakis K, Kalachikov S, Pedley TA, Hauser WA, and Ottman R. Current depression in LGI1 epilepsy mutation carriers.  Epilepsia, 51(9):1685–1690, 2010. PMCID: PMC2939248

  31. Choi H, Heiman GA, Munger-Clary H, Etienne M, Resor SR, and Hauser WA. Seizure remission and relapse in adults with long-standing Intractable Epilepsy: An extended follow-up.  Epilepsy Res., 93, 115-119, 2011.

  32. Shanker VL, Groves, M, Heiman GA, Saunders-Pullman R, Ozelius, L, Palmese C, Raymond D, and Bressman SB.  Mood and cognition in LRRK2 G2019S Parkinson’s disease. Mov Disord., 26: 1875-1880, 2011.

  33. Gorroochurn P, Hodge SE, Heiman GA, and Greenberg DA.  An improved delta-centralization method for population stratification. Hum Hered 71: 180-185, 2011. PMC Journal- In Process.

  34. Fernandez T, Sanders S, Yurkiewicz IR, Ercan-Sencicek AG, Kim YS, Fishman D, Raubeson M, Song Y, Yasuno K, Winson H, Bilguvar K, Glessner J, Chu SH, Leckman J, King RA, Gilbert D, Heiman GA, Tischfield JA, Hoekstra PJ, Devlin B, Hakonarson H, Mane SM, Günel M, and State MW. Rare Copy Number Variants (CNVs) in Tourette Syndrome (TS) are Enriched for Genes in Histaminergic Pathways and Overlap with Risks for Autism. Biol Psychiatry; 71: 392–402, 2012.

  35. Moya PR, Dodman NH, Timpano KR, Rubenstein LM, Rana Z, Fried RL, Reichardt LF, Heiman GA, Tischfield JA, King RA, Galdzicka M, Ginns EI, and Wendland JR. Rare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypes (In press).

  36. Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service S, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis L, Han B, Crane J, Moorjani P, Crenshaw AT, Parkin MA, Reus VI, Lowe TL, Rangel-Lugo M, Chouinard S, Dion Y, Girard S, Cath DC, Smit JH,. King RA, Fernandez T, Leckman JF, Kidd KK, Kidd JR, Pakstis AJ, State MW, Herrera LD, Romero R, Fournier E, Sandor P, Barr CL, Phan N, Gross-Tsur V, Benarroch F, Pollak Y, Budman CL, Bruun RD, Erenberg G, Naarden AL, Lee PC, Weiss N, Kremeyer B, Berrío GB, Campbell D, Silgado JCC, Ochoa WC, Restrepo SCM, Muller H, Duarte AVV, Lyon GJ, Leppert M, Morgan J, Weiss R, Grados MA, Anderson K, Davarya S, Singer H, Walkup J, Jankovic J, Tischfield JA, Heiman GA, Gilbert DL, Hoekstra PJ, Robertson MM, Kurlan R, Liu C, Gibbs JR Singleton A, Hardy  J, Strengman E, Ophoff  R, Wagner M, Moessner R, Mirel DB, Postuma D, Sabatti C, Ruiz-Linares A, Rouleau GA, Purcell S, Heutink P, Oostra BA, McMahon W, Freimer N, Cox NJ, and Pauls DL.  Genome-wide association study of Tourette Syndrome. Mol Psychiatry (Published online August 15, 2012).

  37. Dietrich A, Fernandez TV, King RA, State MW, Tischfield JA, Hoekstra PJ, *Heiman GA; the TIC Genetics Collaborative Group. The Tourette International Collaborative Genetics (TIC Genetics) study, finding the genes causing Tourette syndrome: objectives and methods. Eur Child Adolesc Psychiatry, 2014, Published online, DOI: 10.1007/s00787-014-0543-x. PMC Journal- In Process.


View full list of Dr. Heiman's publications in Google Scholar